Production and Characterization of Carbamazepine Nanocrystals by Electrospraying for Continuous Pharmaceutical Manufacturing
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Production and characterization of carbamazepine nanocrystals by electrospraying for continuous pharmaceutical manufacturing Citation
The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Abstract: In this paper, an electrospray technique followed by annealing at high temperatures was developed to produce nanocrystals of carbamazepine (CBZ), a poorly water-soluble drug, for continuous pharmaceutical manufacturing process. Electrospraying solutions of CBZ in meth...
متن کاملProduction and characterization of carbamazepine nanocrystals by electrospraying for continuous pharmaceutical manufacturing.
In this paper, an electrospray technique followed by annealing at high temperatures was developed to produce nanocrystals of carbamazepine (CBZ), a poorly water-soluble drug, for continuous pharmaceutical manufacturing process. Electrospraying solutions of CBZ in methanol obeys the expected scaling law of current, which is I ∼ Q(1/2) (I, electrical current; Q, flow rate), for liquids with suffi...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Sciences
سال: 2012
ISSN: 0022-3549
DOI: 10.1002/jps.23024